Perry Bible Fellowship
Some of the best comic strips come from student newspapers and only last a little while. Now thanks to the internet the cream can rise to the top. Perry Bible Fellowship is the funniest stuff I've seen in a long time, and we won't be seeing it in the local newspaper. Vengeful unicorns, lizard adultry, interspecies copulation, innapropriate accident investigators, I mean, what more could you ask for?
In the world of highly funny and offensive comic strips, it's right up there with Spacemoose.
PBF Archive (the BIG list)
PBF Randomizer (click objects in the picture for themed strips)